Mark Leadon was born in Minneapolis, Minnesota but grew up in San Diego, California. Later, his parents moved their family to Gainesville, Florida where Mark went to high school and then college at the University of Florida. He grew up around lots of music; especially around his older brothers Bernie Leadon and Tom Leadon. 

Bernie played bluegrass music in San Diego, in rock 'n roll bands in Gainesville, and then moved to L.A. where he played and recorded with Hearts and Flowers, Dillard & Clark, Linda Ronstadt, the Flying Burrito Brothers, and as an original member of the Eagles. Tom played with Tom Petty and Mike Campbell in a Gainesville band called Mudcrutch, then played with Johnny Rivers, Linda Ronstadt, Silver, and others in L.A. 

Tom taught Mark how to play guitar when they were in high school and later Bernie helped Mark pick up the banjo. Mark began playing and recording with bands in Gainesville. After he finished college, he moved to Tallahassee to do engineering work. Mark spent most of his free time playing music in country-rock and bluegrass bands and writing songs. 

He released his first CD of original songs, mark leadon  blue & lonesome in 2001 which featured his bluegrass band Blue & Lonesome.  Mark released his second solo CD, Borderlines, in April 2004 which contains 11 original songs and one by his sister Monica (Leadon) Cooper.  Borderlines features Mark on guitar, banjo, dobro, bass and vocals on tracks mixing bluegrass, country, rock, and blues influences.  Bernie, Tom, and Monica appear on the CD as well as several other guest musicians.  Borderlines was completed and mastered in Nashville with help from Bert Battaglia (re: Bela Fleck, others).  

Mark played for a number of years in Mountain Road, a band that mixed bluegrass and country-rock, including several of Mark's original songs.  Mark is currently performing frequently, primarily as a solo performer, at a number of establishments and events mainly in the Tallahassee area, as well as, in Gainesville and surrounding regions of north Florida (see Performance Schedule).